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Parkinson’s Disease Drugs

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In this lecture Professor Zach Murphy will be presenting on Parkinson's Disease Medications. During this lecture we will start by reviewing the Basal Ganglia Anatomy and Physiology. We will also be reviewing the direct and indirect pathway that is affected with Parkinson's disease. We will then transition into the various drug categories used to treat Parkinson's which includes Levodopa or L-Dopa, Dopamine Agonists, COMT inhibitors, MAO-B inhibitors, Amantadine, and Anticholinergics. We hope you enjoy this lecture!

Table of Contents:

0:00 Lab

0:07 Parkinson’s Disease Medications Introduction

1:20 Basal Ganglia Anatomy

4:23 Direct vs. Indirect Pathway

18:23 Pathophysiology of Parkinson’s Disease

21:26 Drug Classes for Parkinson’s Disease

24:36 Mechanism of Action

38:51 L-Dopa + Carbidopa

1:00:22 Dopamine Agonists

1:06:08 COMT-Inhibitors

1:11:39 MAO-B-Inhibitors

1:20:12 Amantadine

1:27:10 Anticholinergics

1:31:18 PD Medications - Practice Problems

1:36:13 Comment, Like, SUBSCRIBE!

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