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Acute Liver Failure

Pathology
Podcast
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Ninja Nerds!

In this lecture, Professor Zach Murphy will present on Acute Liver Failure (ALF). We will discuss the pathophysiology, highlighting the rapid deterioration of liver function, typically in an individual without pre-existing liver disease, and its causes, including drug-induced liver injury, viral hepatitis, and toxins. The session will transition to a digital presentation focused on the diagnostic approach, including liver function tests, imaging, and criteria for diagnosis. Finally, we will review the management strategies for ALF, emphasizing the importance of supportive care, specific treatments for identifiable causes, and evaluation for liver transplantation. Enjoy the lecture and support us below!

Table of Contents:

0:00 Lab

0:07 Acute Liver Failure Introduction

0:40 Pathophysiology | Direct Parenchymal Liver Injury

7:04 Pathophysiology | Vascular Related Liver Injury

13:16 Complications | Encephalopathy

20:32 Complications | Coagulopathy

24:34 Complications | Hypoglycemia

25:45 Complications | Increased Infection Risk

28:34 Diagnostic Approach

30:45 Treatment

35:13 Comment, Like, SUBSCRIBE!

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